Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703318 | 0.88 | PLAT (0.35) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703371 | 0.88 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL9703676 | 0.87 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703732 | 0.85 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703873 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703753 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703311 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9703898 | 0.79 | DYRK1A (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9703105 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10TOP2A | |
| SCHEMBL9705566 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |