Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.70 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.70 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.70 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.70 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.70 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.70 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.70 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.70 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.70 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.70 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.70 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.70 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.70 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.70 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.70 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704899 | 0.87 | GRIN2D (0.71) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703410 | 0.84 | GRIN2D (0.68) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9705741 | 0.84 | GRIN2D (0.65) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704115 | 0.83 | GRIN2D (0.67) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL6697845 | 0.83 | GRIN2D (1.00) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704240 | 0.82 | EGLN1 (0.70) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704360 | 0.82 | GRIN2D (1.00) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703926 | 0.81 | GRIN2D (0.74) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11256884 | 0.81 | GRIN2D (0.68) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9705036 | 0.80 | GRIN2D (0.66) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |