Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250234 | 0.82 | PLCG1 (1.00) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL1814352 | 0.80 | PLCG1 (0.72) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL31378576 | 0.80 | PLCG1 (0.72) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL31255958 | 0.78 | PLCG1 (0.69) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL5083652 | 0.78 | PLCG1 (0.69) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL9740023 | 0.76 | PLCG1 (0.60) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL15846216 | 0.75 | PLCG1 (0.64) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL4432532 | 0.75 | PLCG1 (0.64) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL1925207 | 0.75 | CA1 (0.62) | PLCG1CA1CA2CA4CA6 | |
| SCHEMBL9704703 | 0.74 | KCNA5 (0.42) | PLCG1L3MBTL1KMT2ATDP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |