SCHEMBL9704209

SCHEMBL9704209

Cc1cc(C=O)c(C)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 13/20 0.47
HPGD P15428 3/20 0.47
GAA P10253 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
POLB P06746 4/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
CTDSP1 Q9GZU7 3/20 0.45
APEX1 P27695 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
CASP6 P55212 2/20 0.45
NSD2 O96028 1/20 0.45
PKM P14618 1/20 0.45
CASP3 P42574 1/20 0.45
RECQL P46063 1/20 0.45
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1250448 0.76 NR1H4 (0.70) LMNAHPGDPOLBMAPT
SCHEMBL1250446 0.76 NR1H4 (0.70) LMNAHPGDPOLBMAPT
SCHEMBL12891998 0.76 NR1H4 (0.70) LMNAHPGDPOLBMAPT
SCHEMBL13568574 0.76 NR1H4 (0.58) LMNASMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL8446536 0.74 GABRB3 (0.45) GABRB3GABRA2GABRB2
SCHEMBL9704022 0.73 GABRB3 (0.41) GABRB3GABRA2GABRB2
SCHEMBL9704377 0.73 GABRB3 (0.38) GABRB3GABRA2GABRB2
SCHEMBL3604258 0.72 NOTUM (0.61) LMNASMN1; SMN2ALDH1A1HPGDGAA
SCHEMBL8446584 0.72 GABRB3 (0.40) GABRB3GABRA2GABRB2
SCHEMBL9704199 0.72 MAPT (0.40) LMNASMN1; SMN2ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed