Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604258 | 0.84 | NOTUM (0.61) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21225466 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17802297 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21225472 | 0.79 | ALDH1A1 (0.62) | NR1H4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL645648 | 0.78 | POLB (0.68) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17802794 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL13568573 | 0.76 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8765504 | 0.76 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9704209 | 0.76 | LMNA (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7825875 | 0.75 | POLB (0.75) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152731-A1 | ANDROGEN RECEPTOR ANTAGONISTS | ALPINE ANDROSCIENCES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| WO-2009148004-A1 | NOVEL COMPOUND AND PHARMACEUTICAL APPLICATION OF SAME | 株式会社 三和化学研究所 (JP) | 2009-12-10 | — | — | WO | disclosed |