Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704328 | 0.86 | GABRA2 (0.50) | NPC1RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7713312 | 0.84 | GABRA2 (0.48) | NPC1RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7711415 | 0.84 | GABRA2 (0.51) | NPC1RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7713362 | 0.84 | GABRA2 (0.48) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9704010 | 0.84 | GABRA2 (0.52) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL9780180 | 0.82 | GABRA2 (0.53) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL9780170 | 0.81 | GABRA2 (0.46) | NPC1RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL9704083 | 0.80 | GABRA2 (0.50) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL9217228 | 0.79 | GABRB3 (0.53) | KDM4ELMNAALDH1A1SMN1; SMN2GABRA2 | |
| SCHEMBL9210112 | 0.78 | GABRA2 (0.50) | ALDH1A1SMN1; SMN2GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013451-A1 | IMIDAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |
| US-5055482-A | Anthelmintic, antiprotozoa, netatocides, pesticides | MAY & BAKER LTD. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0350311-A1 | N-phenylpyrazol-4-yl ether derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1990-01-10 | — | — | EP | disclosed |