Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232323 | 0.92 | — | — | |
| Bicarbonate SCHEMBL9704357 | 0.82 | APLNR (0.30) | APLNR | |
| Bicarbonate SCHEMBL8999424 | 0.82 | MAPK1 (0.31) | APLNR | |
| Bicarbonate SCHEMBL7600398 | 0.81 | MEN1 (0.35) | — | |
| Bicarbonate SCHEMBL5196976 | 0.81 | MEN1 (0.35) | — | |
| Bicarbonate SCHEMBL11211311 | 0.81 | — | — | |
| Bicarbonate SCHEMBL5686126 | 0.81 | MEN1 (0.35) | — | |
| Bicarbonate SCHEMBL8999338 | 0.81 | — | — | |
| Bicarbonate SCHEMBL11336106 | 0.78 | — | — | |
| SCHEMBL11208606 | 0.77 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0075146-B1 | BENZYL ESTERS WITH FLUOROSUBSTITUTED ETHER GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR UTILISATION AS INSECTICIDES | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0075146-A1 | Benzyl esters with fluorosubstituted ether groups, process for their preparation and their utilisation as insecticides | BAYER AG (DE) | 1983-03-30 | — | — | EP | disclosed |
| EP-0008340-A1 | Fluoroalkenyl-substituted cyclopropanecarboxylic acid esters, intermediate products therefor, preparation of the compounds and their utilization as insecticides and/or acaricides | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |