Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704005 | 0.89 | AGTR1 (0.40) | SMN1; SMN2AGTR1AGTR2LMNA | |
| SCHEMBL9704411 | 0.88 | AGTR1 (0.44) | SMN1; SMN2HTTAGTR1AGTR2 | |
| SCHEMBL9705279 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9704688 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9704771 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9705139 | 0.83 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9705886 | 0.83 | AGTR1 (0.40) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9704078 | 0.83 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9704334 | 0.83 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9705934 | 0.83 | AGTR1 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |