Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704307 | 0.95 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9704276 | 0.93 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9704667 | 0.92 | AGTR1 (0.43) | AGTR1AGTR2FAAHCNR1CNR2 | |
| SCHEMBL9705139 | 0.91 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9704653 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9704671 | 0.85 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9704336 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9704740 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9704417 | 0.83 | SMN1; SMN2 (0.38) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9704645 | 0.83 | ENPP2 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |