Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 13/20 | 0.43 |
| ▸ | CCKAR | P32238 | 7/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702894 | 0.88 | CCKBR (0.49) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL9703573 | 0.85 | CCKBR (0.55) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL9702828 | 0.85 | CCKBR (0.48) | PGRCCKBRCCKARGABRA1GABRG2 | |
| SCHEMBL6005194 | 0.70 | CCKBR (0.69) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL6005714 | 0.67 | CCKBR (0.65) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL6005717 | 0.67 | CCKBR (0.65) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL9703671 | 0.66 | PTH1R (0.49) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9705380 | 0.65 | PTH1R (0.50) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL11482488 | 0.63 | GABRA1 (0.70) | CCKBRCCKARGABRA1GABRG2GABRB3 | |
| SCHEMBL1367774 | 0.61 | GABRA1 (0.78) | CCKBRGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091381-A | Detection of peripheral benzodiazepine receptor activity in cell or tissue by labelled compounds using radioisotopes or cytoxic agents | BIOMEASURE, INC. (US) | 1992-02-25 | — | — | US | disclosed |