Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322690 | 0.88 | THRB (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL5098395 | 0.84 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL21313125 | 0.84 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL587102 | 0.84 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1389549 | 0.84 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1755550 | 0.83 | TSHR (0.59) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL13817390 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1047543 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL28747006 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL75506 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5113000-A | Multifunctional, sealers for semiconductors, improved adhesion | TOSHIBA SILICONE CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |