Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704499 | 0.88 | TSHR (0.54) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL27972822 | 0.82 | THRB (0.50) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL1389356 | 0.82 | THRB (0.50) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL9012179 | 0.81 | — | — | |
| Propionic Acid SCHEMBL29930795 | 0.80 | THRB (0.48) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL865331 | 0.79 | TSHR (0.50) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| Butanone SCHEMBL28266670 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL22440408 | 0.78 | THRB (0.57) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL1389549 | 0.78 | TSHR (0.54) | THRBTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL5098395 | 0.78 | TSHR (0.54) | THRBTSHRALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220652-B1 | Method for manufacturing phase gratings of a combination pattern-refraction modification type | KURARAY CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4777116-A | RADIATION OF A MASKED THIN FILM OF A (METH)ACRYLATE POLYMER AND REACTIVE AROMATIC ALDEHYDE AND KETONE | KURARAY CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0220652-A2 | Method for manufacturing phase gratings of a combination pattern-refraction modification type | Kuraray Co., Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |