Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096437 | 0.80 | THRB (0.53) | ALDH1A1LMNATAAR1LPLLIPG | |
| SCHEMBL8925998 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19TP53ALDH1A1LMNA | |
| SCHEMBL475215 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19TP53ALDH1A1LMNA | |
| SCHEMBL11725689 | 0.78 | TAAR1 (0.52) | SMN1; SMN2CYP2C19TP53ALDH1A1LMNA | |
| SCHEMBL1047372 | 0.77 | THRB (0.50) | SMN1; SMN2TP53ALDH1A1LMNAMAPT | |
| Ethylene SCHEMBL27468236 | 0.76 | TP53 (0.59) | SMN1; SMN2TP53ALDH1A1LMNATAAR1 | |
| SCHEMBL36295 | 0.76 | TP53 (0.67) | SMN1; SMN2TP53ALDH1A1LMNATAAR1 | |
| SCHEMBL30878 | 0.76 | CA12 (0.61) | SMN1; SMN2TP53ALDH1A1LMNAMAPT | |
| SCHEMBL3138590 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19TP53ALDH1A1LMNA | |
| SCHEMBL11504608 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009463-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | claimed |
| WO-2009051772-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2009-04-23 | — | — | WO | claimed |
| US-4707161-A | Lightfastness of dyeings obtained with acid dyes or metal complex dyes on polyamides: treatment with copper hydroxamates | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-17 | — | — | US | claimed |
| US-4562204-A | ANTITUMOR, ANTILEUKEMIA AGENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-12-31 | — | — | US | claimed |
| EP-0097023-A2 | Prostaglandin D derivatives, process for their preparation and compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-12-28 | — | — | EP | claimed |
| CN-111315828-B | Composition, cured product, optical filter, and method for producing cured product | 株式会社艾迪科 | 2023-09-29 | — | — | CN | disclosed |
| CN-112154167-B | Composition, cured product, optical filter, and method for producing cured product | 株式会社艾迪科 | 2023-08-22 | — | — | CN | disclosed |
| CN-107918247-B | Colored curable resin composition | 住友化学株式会社 | 2022-03-18 | — | — | CN | disclosed |
| CN-106019840-B | Colored curable resin composition | 东友精细化工有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112154167-A | Composition, cured product, optical filter, and method for producing cured product | 株式会社艾迪科 | 2020-12-29 | — | — | CN | disclosed |
| CN-111315828-A | Composition, cured product, optical filter, and method for producing cured product | 株式会社艾迪科 | 2020-06-19 | — | — | CN | disclosed |
| EP-3658112-A1 | ACTIVE SUBSTANCE COMBINATIONS OF N-(4-AMINO-2-METHYLQUINOLINE-6-YL)-2-((4-ETHYLPHENOXY)METHYL) AND ONE OR MORE COSMETICALLY OR DERMATOLOGICALLY ACCEPTABLE PRESERVATIVES AND/OR PRESERVATIVE AUXILIARIES | Beiersdorf AG (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-4367237-A | THIOPGI-1 DERIVATIVES; OXYTOCICS; PREFERENTIAL | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| US-4351846-A | 3-Hydroxy and 3-oxo-prostaglandin analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-09-28 | — | — | US | disclosed |
| EP-0044711-A1 | 9,11-Methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-27 | — | — | EP | disclosed |
| EP-0017132-B1 | DYESTUFFS, THEIR PREPARATION AND UTILISATION | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4284581-A | LITHIUM 1,1'-BINAPHTHYL-2,2'-DIOXYALUMINUM HYDRIDE, REDUCING AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0017132-A1 | Dyestuffs, their preparation and utilisation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |
| US-4031082-A | Process for preparing 3-acycloxymethyl-2-cephem compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4029651-A | ESTERIFICATION | ELI LILLY AND COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009463-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | FNTA, GGPS1, PTAR1 | SMN1; SMN2 3969/4885CYP2C19 3340/4885TP53 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.