SCHEMBL9704529

SCHEMBL9704529

CCC(=O)N(N)c1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.44
ESR2 Q92731 7/20 0.44
CA2 P00918 3/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
ALDH1A1 P00352 4/20 0.39
ESRRG P62508 3/20 0.39
TSHR P16473 3/20 0.39
CYP3A4 P08684 2/20 0.39
HIF1A Q16665 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
CHRM1 P11229 2/20 0.39
SLC6A2 P23975 2/20 0.39
MEN1 O00255 1/20 0.39
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10878247 0.85 HSD17B3 (0.48) ESR1ESR2CA2CA12CA1
SCHEMBL10785489 0.84 ALDH1A1 (0.47) ALDH1A1TSHRCYP3A4SMN1; SMN2LMNA
SCHEMBL12961531 0.82 HSD17B10 (0.30) TP53HSD17B10
SCHEMBL3388559 0.82 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4SMN1; SMN2LMNA
SCHEMBL28157600 0.79 KDM4E (0.44) CA2CA12CA1CA7CA9
SCHEMBL14466606 0.78 NR1I2 (0.38) ALDH1A1TSHRSMN1; SMN2LMNAMEN1
SCHEMBL28191917 0.78 KIF11 (0.41) ALDH1A1TSHRCYP3A4LMNAMEN1
SCHEMBL28507452 0.78 ESR1 (0.42) ESR1ESR2CA2CA12CA1
SCHEMBL5663915 0.77 ESR1 (0.41) ESR1ESR2CA2CA12CA1
SCHEMBL29009099 0.77 EPHX1 (0.47) ESR1TSHRLMNACYP2C9ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992008747-A1 NOVEL ANTIOXIDANT AND LIGHT STABILIZER BOUND OLIGOMER SYSTEMS FOR RADIATION CURED MATERIALS DSM N.V. (NL) 1992-05-29 WO claimed