Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990771 | 0.84 | ALDH1A1 (0.55) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29434710 | 0.79 | POLB (0.72) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL2094424 | 0.79 | POLB (0.72) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29427895 | 0.77 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL10168722 | 0.77 | POLB (0.53) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL31664113 | 0.76 | POLB (0.52) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL1058989 | 0.76 | POLB (0.52) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL30214477 | 0.75 | POLB (0.51) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29794411 | 0.74 | POLB (0.50) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28783740 | 0.74 | POLB (0.50) | POLBALDH1A1SMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-0482481-A1 | Method for the preparation of 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepines | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1992-04-29 | — | — | EP | disclosed |