Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550111 | 0.67 | ALDH1A1 (0.40) | KDM4ECYP3A4USP2TSHRALDH1A1 | |
| SCHEMBL20658087 | 0.64 | USP2 (0.32) | USP2TSHR | |
| SCHEMBL11374297 | 0.61 | — | — | |
| SCHEMBL11109760 | 0.61 | — | — | |
| SCHEMBL800271 | 0.61 | KDM4E (0.46) | KDM4ECYP3A4USP2TSHRALDH1A1 | |
| SCHEMBL92892 | 0.61 | — | — | |
| SCHEMBL775496 | 0.59 | CA1 (0.33) | KDM4ECYP3A4CA1 | |
| SCHEMBL6910515 | 0.58 | — | — | |
| SCHEMBL17322566 | 0.58 | — | — | |
| SCHEMBL1149141 | 0.58 | KDM4E (0.42) | KDM4ECYP3A4USP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017450-A1 | BIS-METHYLENE ETHER PYRIDINIUM COMPOUND PREPARATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992017450-A1 | BIS-METHYLENE ETHER PYRIDINIUM COMPOUND PREPARATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5130438-A | Reaction of bis(methylsulfonoxymethyl)ether with pyridino-2-aldoxime and then isonicotinamide followed by ino exchanging chloride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-07-14 | — | — | US | disclosed |
| US-5130438-A | Reaction of bis(methylsulfonoxymethyl)ether with pyridino-2-aldoxime and then isonicotinamide followed by ino exchanging chloride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-07-14 | — | — | US | disclosed |