Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492502 | 0.96 | SIGMAR1 (0.66) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL9772450 | 0.90 | SIGMAR1 (0.61) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL7963090 | 0.90 | SIGMAR1 (0.61) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL9748062 | 0.83 | OPRK1 (1.00) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL9748668 | 0.83 | OPRK1 (1.00) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL14367928 | 0.83 | OPRK1 (1.00) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL9496397 | 0.83 | SIGMAR1 (0.68) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7077002 | 0.82 | OPRK1 (1.00) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7077006 | 0.82 | OPRK1 (1.00) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 | |
| 1,2-Dichlorobenzene SCHEMBL9701834 | 0.81 | SIGMAR1 (0.74) | SIGMAR1OPRM1OPRD1OPRK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130329-A | Amino, amide substituted compounds | ROUSSEL UCLAF (FR) | 1992-07-14 | — | — | US | disclosed |
| US-5068244-A | Benzcarbocyclic amides with nitro groups | ROUSSEL UCLAF (FR) | 1991-11-26 | — | — | US | disclosed |