Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704777 | 0.94 | AGTR1 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL9705913 | 0.92 | KDM4E (0.41) | — | |
| SCHEMBL9705198 | 0.92 | PPARG (0.41) | PPARG | |
| SCHEMBL9703974 | 0.91 | KDM4E (0.46) | — | |
| SCHEMBL9704034 | 0.90 | ALDH1A1 (0.45) | — | |
| SCHEMBL9704706 | 0.89 | PPARG (0.43) | PPARG | |
| SCHEMBL9705244 | 0.88 | AGTR1 (0.42) | — | |
| SCHEMBL9705284 | 0.86 | AGTR1 (0.36) | — | |
| SCHEMBL9705809 | 0.85 | AGTR1 (0.45) | — | |
| SCHEMBL9705017 | 0.85 | AGTR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |