Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701890 | 0.84 | XIAP (0.40) | ARLMNASMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL9702850 | 0.82 | AR (0.36) | ARPARP10ALDH1A1ESR1LMNA | |
| SCHEMBL10396879 | 0.82 | HPGD (0.41) | ARALDH1A1LMNASMN1; SMN2CARM1 | |
| SCHEMBL9368279 | 0.81 | BCL2 (0.41) | ALDH1A1LMNA | |
| SCHEMBL9702892 | 0.77 | PARP10 (0.43) | ARPARP10ALDH1A1ESR1LPAR1 | |
| SCHEMBL25962922 | 0.71 | HTR2A (0.49) | ARPARP10ALDH1A1GCKHTR2A | |
| SCHEMBL10417101 | 0.70 | ALDH1A1 (0.45) | PARP10ALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL15472270 | 0.70 | PARP10 (0.51) | PARP10ALDH1A1ESR1LPAR1LPAR5 | |
| SCHEMBL9728476 | 0.69 | ALDH1A1 (0.33) | PARP10ALDH1A1ESR1GCKKDM4E | |
| SCHEMBL9703462 | 0.69 | AR (0.36) | ARPARP10ALDH1A1ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481921-A1 | Substituted carbodiimides and thio-ureas and their utilisation against insects | CIBA-GEIGY AG (CH) | 1992-04-22 | — | — | EP | disclosed |