Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704630 | 0.84 | AR (0.38) | SLC6A4HTR2AKCNH2ARL3MBTL1 | |
| SCHEMBL9704788 | 0.82 | XIAP (0.37) | XIAPSLC6A4HTR2AKCNH2AR | |
| SCHEMBL10396879 | 0.82 | HPGD (0.41) | SLC6A4HTR2AARL3MBTL1LMNA | |
| SCHEMBL9368279 | 0.81 | BCL2 (0.41) | GABRA1GABRB2LMNA | |
| SCHEMBL9702388 | 0.77 | XIAP (0.45) | XIAPSLC6A4HTR2AKCNH2AR | |
| SCHEMBL5018840 | 0.71 | XIAP (0.54) | XIAPSLC6A4HTR2AKCNH2AR | |
| SCHEMBL31544426 | 0.69 | MGLL (0.43) | XIAPSLC6A4HTR2AKCNH2AR | |
| SCHEMBL11435322 | 0.69 | P2RX3 (0.49) | XIAPSLC6A4HTR2AKCNH2AR | |
| SCHEMBL8845542 | 0.69 | LTA4H (0.40) | — | |
| SCHEMBL1457748 | 0.69 | GABRA1 (0.48) | SLC6A4GABRA1GABRB2SLC6A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481921-A1 | Substituted carbodiimides and thio-ureas and their utilisation against insects | CIBA-GEIGY AG (CH) | 1992-04-22 | — | — | EP | disclosed |