Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210103 | 0.84 | GAA (0.44) | LMNAALDH1A1KDM4EGAATDP1 | |
| SCHEMBL4971064 | 0.84 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL14036616 | 0.82 | LMNA (0.47) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL18319116 | 0.81 | LMNA (0.54) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL13324326 | 0.81 | KDM4E (0.49) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL31634966 | 0.80 | LMNA (0.67) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL22945621 | 0.80 | LMNA (0.67) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL670086 | 0.80 | LMNA (0.77) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL18319253 | 0.79 | LMNA (0.51) | LMNAALDH1A1KDM4EGAAPOLB | |
| SCHEMBL17967819 | 0.79 | PTGDR2 (0.54) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166398-A | Anticholesterol agents or atherosclerosis | WARNER-LAMBERT CO. (US) | 1992-11-24 | — | — | US | disclosed |