SCHEMBL9704735

SCHEMBL9704735

Cc1c(CO)c(Cl)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRB3 P28472 15/20 0.42
GABRA2 P47869 13/20 0.42
GABRB2 P47870 13/20 0.42
GABRP O00591 3/20 0.35
GABRD O14764 3/20 0.35
GABRA1 P14867 3/20 0.35
GABRB1 P18505 3/20 0.35
GABRG2 P18507 3/20 0.35
GABRA5 P31644 3/20 0.35
GABRA3 P34903 3/20 0.35
GABRA4 P48169 3/20 0.35
GABRE P78334 3/20 0.35
GABRA6 Q16445 3/20 0.35
GABRG1 Q8N1C3 3/20 0.35
GABRG3 Q99928 3/20 0.35
GABRQ Q9UN88 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704377 0.73 GABRB3 (0.38) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL319759 0.73 ALDH1A1 (0.42) GABRB3GABRA2GABRB2
SCHEMBL9703384 0.72 GABRB3 (0.51) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL8446536 0.71 GABRB3 (0.45) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9704497 0.69 GABRB3 (0.46) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9704037 0.68 GABRB3 (0.44) GABRB3GABRA2GABRB2
SCHEMBL8321562 0.67 PDE2A (0.44) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9218868 0.67 GABRB3 (0.50) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL8331433 0.66 GABRB3 (0.61) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL22042180 0.66 GABRB3 (0.51) GABRB3GABRA2GABRB2GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed