Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21871759 | 0.93 | CTRC (0.62) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL14886507 | 0.93 | MEN1 (0.67) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL28046975 | 0.89 | CTRC (0.69) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL4347883 | 0.89 | CTRC (0.69) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL17996254 | 0.89 | CTRC (0.69) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL23624440 | 0.89 | CTRC (0.69) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL32681303 | 0.87 | CTRC (0.56) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL17866610 | 0.87 | MEN1 (0.65) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL9705291 | 0.86 | CTRC (0.65) | CTRCL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL16716532 | 0.85 | MEN1 (0.66) | CTRCL3MBTL1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |