SCHEMBL9705291

SCHEMBL9705291

Oc1cc(-c2ccccc2)nc(-c2ccc(Cl)cc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 2/20 0.65
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
NTSR1 P30989 1/20 0.56
L3MBTL1 Q9Y468 3/20 0.53
HPGD P15428 3/20 0.53
ALDH1A1 P00352 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP1A2 P05177 1/20 0.52
ADORA3 P0DMS8 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ADORA2A P29274 1/20 0.49
ADORA1 P30542 1/20 0.49
MAPT P10636 4/20 0.49
KDM4E B2RXH2 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.48
SQOR Q9Y6N5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14802089 0.88 MEN1 (0.63) CTRCMEN1KMT2ANTSR1L3MBTL1
SCHEMBL9704830 0.86 CTRC (0.66) CTRCMEN1KMT2AL3MBTL1HPGD
SCHEMBL23624440 0.84 CTRC (0.69) CTRCMEN1KMT2AL3MBTL1HPGD
SCHEMBL28046975 0.84 CTRC (0.69) CTRCMEN1KMT2AL3MBTL1HPGD
SCHEMBL4347883 0.84 CTRC (0.69) CTRCMEN1KMT2AL3MBTL1HPGD
SCHEMBL17996254 0.84 CTRC (0.69) CTRCMEN1KMT2AL3MBTL1HPGD
SCHEMBL9848060 0.83 CYP19A1 (0.55) CTRCMEN1KMT2ANPC1RAB9A
SCHEMBL4808050 0.80 MEN1 (0.61) CTRCMEN1KMT2ANTSR1L3MBTL1
SCHEMBL16716532 0.80 MEN1 (0.66) CTRCMEN1KMT2ANTSR1L3MBTL1
SCHEMBL15395065 0.80 MEN1 (0.83) CTRCMEN1KMT2ANTSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463492-A1 2,6-Diarylpyridin derivatives BAYER AG (DE) 1992-01-02 EP disclosed