Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532075 | 0.91 | AGTR1 (0.33) | AGTR1AGTR2TMEM97SIGMAR1BRS3 | |
| SCHEMBL9705048 | 0.89 | AGTR1 (0.34) | AGTR1AGTR2TMEM97SIGMAR1BRS3 | |
| SCHEMBL9531406 | 0.88 | BRS3 (0.37) | AGTR1AGTR2TMEM97SIGMAR1BRS3 | |
| SCHEMBL9531741 | 0.85 | AGTR1 (0.33) | AGTR1AGTR2BRS3 | |
| SCHEMBL9532201 | 0.83 | AGTR1 (0.33) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL9531666 | 0.81 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9554190 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9554102 | 0.79 | AGTR1 (0.40) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL9535036 | 0.79 | AGTR1 (0.37) | AGTR1AGTR2BRS3SLC33A1MME | |
| SCHEMBL9530491 | 0.79 | AGTR1 (0.32) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |