Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704954 | 0.89 | AGTR1 (0.34) | AGTR1AGTR2SLC33A1TMEM97SIGMAR1 | |
| SCHEMBL9532075 | 0.88 | AGTR1 (0.33) | AGTR1AGTR2TMEM97SIGMAR1BRS3 | |
| SCHEMBL9531406 | 0.87 | BRS3 (0.37) | AGTR1AGTR2TMEM97SIGMAR1BRS3 | |
| SCHEMBL9705208 | 0.86 | AGTR1 (0.33) | AGTR1AGTR2BRS3 | |
| SCHEMBL9530841 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL9530681 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9532201 | 0.80 | AGTR1 (0.33) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL9535036 | 0.80 | AGTR1 (0.37) | AGTR1AGTR2SLC33A1BRS3 | |
| SCHEMBL9554414 | 0.79 | AGTR2 (0.39) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7830100 | 0.78 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |