Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310988 | 0.85 | GABRB3 (0.55) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10560642 | 0.84 | GABRB3 (0.54) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9209147 | 0.83 | GABRB3 (0.53) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| Ammonia Solution, Strong SCHEMBL10557787 | 0.83 | GABRB3 (0.53) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9211791 | 0.83 | NPC1 (0.63) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9705715 | 0.81 | GABRB3 (0.59) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10400843 | 0.77 | NPC1 (0.59) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9703352 | 0.75 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9212439 | 0.75 | GABRB3 (0.46) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10769999 | 0.74 | GABRB3 (0.51) | SMN1; SMN2GABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013451-A1 | IMIDAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |