Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435773 | 0.90 | GABRP (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9211427 | 0.80 | CYP3A4 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9310988 | 0.80 | GABRB3 (0.55) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8432858 | 0.79 | TDP1 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9206366 | 0.79 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9203720 | 0.79 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10560642 | 0.77 | GABRB3 (0.54) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Ammonia Solution, Strong SCHEMBL10557787 | 0.76 | GABRB3 (0.53) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9211791 | 0.76 | NPC1 (0.63) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9209147 | 0.76 | GABRB3 (0.53) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544218-B1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5266556-A | Herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0544218-A1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |