Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704935 | 0.98 | KDM4E (0.56) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9702712 | 0.98 | KDM4E (0.56) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9704095 | 0.95 | ALDH1A1 (0.50) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9703126 | 0.94 | KDM4E (0.51) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9702960 | 0.94 | KDM4E (0.55) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9702375 | 0.92 | KDM4E (0.54) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9703146 | 0.90 | RAB9A (0.46) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9702885 | 0.89 | KDM4E (0.66) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL15164266 | 0.87 | KDM4E (0.68) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL9702884 | 0.87 | KDM4E (0.68) | KDM4ERAB9AALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |