Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769367 | 0.96 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12871889 | 0.96 | ALDH1A1 (0.33) | ALDH1A1 | |
| Bicarbonate SCHEMBL10878930 | 0.81 | — | — | |
| Bicarbonate SCHEMBL9324063 | 0.80 | — | — | |
| Bicarbonate SCHEMBL9323117 | 0.80 | — | — | |
| Bicarbonate SCHEMBL10876839 | 0.77 | — | — | |
| SCHEMBL10881509 | 0.77 | — | — | |
| Bicarbonate SCHEMBL4370597 | 0.76 | APLNR (0.36) | — | |
| SCHEMBL11287593 | 0.76 | GLA (0.30) | — | |
| SCHEMBL9421765 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | claimed |
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0011695-B1 | SUBSTITUTED CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR DERIVATIVES; THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF INSECTICIDES AND ACARICIDES | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |