Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705078 | 0.94 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9034921 | 0.91 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9733398 | 0.88 | KMT2A (0.34) | AGTR1AGTR2 | |
| SCHEMBL9036503 | 0.87 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9037085 | 0.87 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9037161 | 0.86 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9036141 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9705108 | 0.86 | ADORA2A (0.35) | ADORA2AADORA2BAGTR1AGTR2 | |
| SCHEMBL9733524 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9733915 | 0.85 | AGTR1 (0.43) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | claimed |
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |