Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533442 | 0.92 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9705106 | 0.88 | ADORA2A (0.35) | AGTR1AGTR2 | |
| SCHEMBL9705078 | 0.85 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9553524 | 0.83 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9554176 | 0.82 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9554396 | 0.82 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9554210 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9037085 | 0.82 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9554072 | 0.82 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9530897 | 0.81 | AGTR2 (0.37) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |