Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637985 | 0.83 | ALOX15 (0.43) | SMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL10893135 | 0.83 | KCNH2 (0.48) | CHRM2CHRM1DRD3KDM4ECYP1A2 | |
| SCHEMBL2671430 | 0.80 | USP2 (0.42) | HTTALDH1A1SLC6A4 | |
| SCHEMBL11679757 | 0.79 | TAAR1 (0.47) | CHRM2CHRM1DRD3SIGMAR1DRD1 | |
| SCHEMBL9746244 | 0.79 | ADRB2 (0.43) | KDM4EALDH1A1SLC6A4 | |
| SCHEMBL11687676 | 0.77 | TSHR (0.49) | KDM4ELTA4HALDH1A1TSHR | |
| SCHEMBL24486783 | 0.76 | CHRM2 (0.56) | CHRM2CHRM1DRD3KDM4ESMN1; SMN2 | |
| SCHEMBL11675409 | 0.76 | TSHR (0.50) | HTTLMNAALDH1A1TSHRTDP1 | |
| SCHEMBL11169835 | 0.76 | MEN1 (0.38) | KDM4ESMN1; SMN2LMNAALDH1A1SLC6A4 | |
| SCHEMBL11677328 | 0.76 | AOC3 (0.51) | CHRM2CHRM1DRD3SIGMAR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214852-B1 | PERFLUOROAMINOETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5049670-A | Pour point | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929725-A | NONFLAMMABLE, HYDRAULIC FLUIDS | MOORE GEORGE G I (US) | 1990-05-29 | — | — | US | disclosed |
| US-4788339-A | HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-29 | — | — | US | disclosed |