Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23137518 | 0.84 | VCAM1 (0.46) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL56482 | 0.78 | VCAM1 (0.41) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26626652 | 0.77 | GRIN2D (0.44) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30168968 | 0.76 | TDP1 (0.39) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL345622 | 0.76 | TDP1 (0.39) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18894107 | 0.75 | VCAM1 (0.47) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| Potassium Ion SCHEMBL5156009 | 0.75 | GRIN2D (0.39) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31321220 | 0.75 | VCAM1 (0.47) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25252333 | 0.75 | GPR35 (0.41) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL670932 | 0.74 | VCAM1 (0.50) | VCAM1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506907-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ-ERFINDUNGEN Verwaltungsgesellschaft m.b.H. (AT) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992007837-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ LTD. (CH) | 1992-05-14 | — | — | WO | disclosed |