Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.80 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.80 |
| ▸ | PPARG | P37231 | 4/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851819 | 0.93 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL7021447 | 0.89 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9853641 | 0.89 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL8392912 | 0.87 | AGTR1 (0.83) | AGTR1AGTR2PPARG | |
| SCHEMBL8393637 | 0.86 | PPARG (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9705301 | 0.86 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL9335305 | 0.86 | AGTR1 (0.85) | AGTR1AGTR2PPARG | |
| SCHEMBL7048452 | 0.86 | AGTR1 (0.82) | AGTR1AGTR2PPARG | |
| SCHEMBL8396736 | 0.85 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL8396130 | 0.85 | AGTR1 (0.80) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | claimed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |