Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 1.00 |
| ▸ | AGTR2 | P50052 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 4/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854881 | 0.90 | AGTR1 (0.81) | AGTR1AGTR2PPARG | |
| SCHEMBL7021447 | 0.89 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL7851819 | 0.89 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL9705296 | 0.89 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL8392912 | 0.86 | AGTR1 (0.83) | AGTR1AGTR2PPARG | |
| SCHEMBL8391692 | 0.86 | AGTR1 (0.83) | AGTR1AGTR2PPARG | |
| SCHEMBL8393637 | 0.86 | PPARG (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL8396598 | 0.85 | AGTR1 (0.79) | AGTR1AGTR2PPARG | |
| SCHEMBL9335305 | 0.85 | AGTR1 (0.85) | AGTR1AGTR2PPARG | |
| SCHEMBL9123448 | 0.85 | AGTR1 (0.79) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |