Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563211 | 0.86 | GAA (0.47) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL12264964 | 0.83 | MEN1 (0.55) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL32681303 | 0.80 | CTRC (0.56) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL4657928 | 0.79 | ALOX5 (0.47) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL32681317 | 0.78 | CTRC (0.54) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL16376441 | 0.77 | MEN1 (0.60) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL17756652 | 0.77 | MEN1 (0.60) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL13559277 | 0.77 | MAPT (0.53) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL1256026 | 0.77 | L3MBTL1 (0.55) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL2614936 | 0.77 | CXCL12 (0.54) | NPC1RAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | claimed |
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |