Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704384 | 0.95 | AGTR1 (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704332 | 0.94 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9704724 | 0.92 | PPARG (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705230 | 0.91 | PPARG (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704302 | 0.90 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704636 | 0.89 | PPARG (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705254 | 0.88 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9704422 | 0.87 | AGTR2 (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL9704745 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9704468 | 0.85 | AGTR1 (0.41) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |