Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699970 | 0.81 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL16783778 | 0.75 | ADORA3 (0.39) | ADORA2ACDK1 | |
| SCHEMBL30668845 | 0.72 | CYP11B1 (0.37) | EGFRADORA2ACYP11B1CYP11B2 | |
| SCHEMBL20637862 | 0.72 | CYP11B1 (0.37) | EGFRADORA2ACYP11B1CYP11B2 | |
| SCHEMBL5857609 | 0.72 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL63354 | 0.71 | CDK1 (0.61) | ADORA2ACDK1 | |
| SCHEMBL17892682 | 0.71 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28083639 | 0.70 | CYP1A2 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL13012219 | 0.70 | TYMP (0.45) | — | |
| SCHEMBL4599284 | 0.69 | PI4KA (0.32) | PI4KAPI4K2BPI4K2API4KBCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |