Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119629 | 0.79 | CDK1 (0.72) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL31711721 | 0.79 | HTT (0.75) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL4599282 | 0.78 | CCNB2 (0.36) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL20097160 | 0.77 | CCNB2 (0.69) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL21311333 | 0.76 | CCNB2 (0.65) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL20097047 | 0.76 | CCNB2 (0.65) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL20097149 | 0.76 | CCNB2 (1.00) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL457250 | 0.75 | HTT (0.67) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL20119633 | 0.75 | HTT (0.67) | CDK1CCNB2CCNB1CCNB3HTT | |
| SCHEMBL457947 | 0.75 | HTT (0.70) | CDK1CCNB2CCNB1CCNB3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926703-B1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS BV (NL) | 2013-01-09 | — | — | EP | disclosed |
| US-8129562-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2012-03-06 | — | — | US | disclosed |
| US-20110124726-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS B.V. | 2011-05-26 | — | — | US | disclosed |
| US-7906496-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2011-03-15 | — | — | US | disclosed |
| US-20090258887-A1 | Novel Carboxylic Acid Derivatives | DSM ASSETS B.V. (NL) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258887-A1 | Novel Carboxylic Acid Derivatives | AADAC, ALDH7A1, DDC | CDK1 4565/4885CCNB2 3257/4885CCNB1 3654/4885 |
| US-20110124726-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | AADAC, ALDH7A1, ALDH18A1 | CDK1 4460/4885CCNB2 3251/4885CCNB1 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.