Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708542 | 0.88 | MAPT (0.32) | ALDH1A1MAPTMAOASMN1; SMN2CYP1A2 | |
| SCHEMBL8711173 | 0.80 | GSK3B (0.32) | ALDH1A1MAPT | |
| SCHEMBL997179 | 0.78 | HPD (0.40) | KCNH2ALDH1A1MAPTCHRM5TLR2 | |
| SCHEMBL9704964 | 0.71 | KMT2A (0.35) | ALDH1A1MAPTCHRM5MPIPHOSPHO1 | |
| SCHEMBL13433933 | 0.70 | KCNH2 (0.38) | KCNH2TXNRD1ALDH1A1MAPTMAOA | |
| SCHEMBL28550353 | 0.68 | SMN1; SMN2 (0.39) | TXNRD1ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL13433904 | 0.67 | CYP1A2 (0.43) | TXNRD1ALDH1A1MAPTMAOASMN1; SMN2 | |
| SCHEMBL9441394 | 0.67 | HPD (0.36) | KCNH2ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL31191337 | 0.65 | CYP1A2 (0.58) | ALDH1A1MAPTPTGS2SMN1; SMN2CYP1A2 | |
| SCHEMBL31191330 | 0.65 | PDGFRB (0.53) | TXNRD1ALDH1A1MAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506907-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ-ERFINDUNGEN Verwaltungsgesellschaft m.b.H. (AT) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992007837-A1 | HETEROCYCLIC DIONE DERIVATIVES AS PESTICIDES AND PLANT GROWTH REGULATORS | SANDOZ LTD. (CH) | 1992-05-14 | — | — | WO | disclosed |