Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191337 | 0.88 | CYP1A2 (0.58) | CYP1A2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31191330 | 0.87 | PDGFRB (0.53) | CYP1A2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL14099278 | 0.83 | ALDH1A1 (0.55) | CYP1A2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL28550353 | 0.80 | SMN1; SMN2 (0.39) | CYP1A2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2977227 | 0.79 | HPD (0.52) | CYP1A2SMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL25987854 | 0.77 | RAB9A (0.41) | CYP1A2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL13433933 | 0.77 | KCNH2 (0.38) | SMN1; SMN2MEN1KMT2AMITFTHRB | |
| SCHEMBL30410464 | 0.77 | CYP1A2 (0.50) | CYP1A2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2994232 | 0.77 | CYP1A2 (0.50) | CYP1A2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3483129 | 0.76 | KMT2A (0.56) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819983-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLPROPANONES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-04 | — | — | EP | disclosed |
| US-7683092-B2 | Crystalline forms of antidiabetic compounds | MERCK SHARP & DOHME CORP. (US) | 2010-03-23 | — | — | US | disclosed |
| US-7683092-B2 | Crystalline forms of antidiabetic compounds | MERCK SHARP & DOHME CORP. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080221198-A1 | Novel Crystalline Forms of Antidiabetic Compounds | MERCK SHARP & DOHME CORP. | 2008-09-11 | — | — | US | disclosed |
| US-20080221198-A1 | Novel Crystalline Forms of Antidiabetic Compounds | MERCK SHARP & DOHME CORP. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221198-A1 | Novel Crystalline Forms of Antidiabetic Compounds | FFAR2, PPARG, PPARA | CYP1A2 626/4885SMN1; SMN2 4850/4885NPC1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.