Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 4/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662785 | 1.00 | MAPT (0.57) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL3718763 | 0.92 | DGKA (0.62) | MAPTPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL31108940 | 0.89 | MAPT (0.58) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL30701946 | 0.89 | MAPT (0.58) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL16266862 | 0.88 | MAPT (0.57) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL30932019 | 0.87 | MAPT (0.64) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL22579234 | 0.87 | MAPT (0.64) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL28452236 | 0.84 | MAPT (0.60) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL7612157 | 0.84 | MAPT (0.60) | MAPTMAPK1LMNAKDM4EDUSP3 | |
| SCHEMBL10477902 | 0.84 | LMNA (0.68) | MAPTLMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214501-B1 | EMULSION COMPOSITIONS FOR ADMINISTRATION OF SPARINGLY WATER SOLUBLE IONIZABLE BASIC HYDROPHOBIC DRUGS | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |
| EP-0215313-B1 | EMULSION COMPOSITIONS FOR THE PARENTERAL AND/OR ORAL ADMINISTRATION OF SPARINGLY WATER SOLUBLE IONIZABLE HYDROPHOBIC DRUGS | AMERICAN CYANAMID COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-4816247-A | FOR INJECTIONS | AMERICAN CYANAMID COMPANY (US) | 1989-03-28 | — | — | US | disclosed |
| US-4784845-A | FAT EMULSIONS WITH BENZYL ALCOHOL FOR DRUGS | AMERICAN CYANAMID COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0215313-A2 | Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs | AMERICAN CYANAMID COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0214501-A2 | Emulsion compositions for administration of sparingly water soluble ionizable basic hydrophobic drugs | AMERICAN CYANAMID COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |