Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018868 | 0.84 | POLB (0.53) | HPGDPOLBHTTTTRNPC1 | |
| SCHEMBL14060463 | 0.82 | HPGD (0.63) | HPGDPOLBHTTNTRK2CA12 | |
| SCHEMBL3321012 | 0.82 | NTRK2 (0.65) | HPGDPOLBHTTNTRK2KMT2A | |
| SCHEMBL6293010 | 0.81 | FABP4 (0.64) | HPGDPOLBHTTNTRK2GAA | |
| SCHEMBL1669128 | 0.81 | KDM4E (0.59) | HPGDPOLBHTTNTRK2GAA | |
| SCHEMBL9863129 | 0.81 | HPGD (0.76) | HPGDPOLBHTTNPC1GAA | |
| SCHEMBL6290092 | 0.80 | HPGD (1.00) | HPGDPOLBHTTNPC1KMT2A | |
| SCHEMBL18542445 | 0.79 | NTRK2 (0.57) | HPGDPOLBHTTNTRK2GAA | |
| SCHEMBL5878629 | 0.79 | HPGD (0.53) | HPGDPOLBHTTNTRK2GAA | |
| SCHEMBL9705957 | 0.78 | NTRK2 (0.49) | HPGDPOLBHTTNTRK2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4861791-A | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents | STERLING DRUG INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |