Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826511 | 0.77 | CD44 (0.39) | CYP3A4TSHRMEN1KMT2APTGS2 | |
| SCHEMBL11692564 | 0.76 | EDNRA (0.36) | P2RY4THRBALDH1A1CYP3A4HPGD | |
| SCHEMBL11690367 | 0.76 | EDNRA (0.38) | P2RY4THRBALDH1A1CYP3A4HPGD | |
| SCHEMBL10589162 | 0.75 | THRB (0.38) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL11035060 | 0.73 | TTR (0.40) | THRBALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL5161924 | 0.72 | SLC40A1 (0.36) | THRBCYP3A4HPGDTSHRHSD17B10 | |
| Water SCHEMBL31670348 | 0.71 | SLC40A1 (0.36) | THRBCYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL829160 | 0.71 | CD44 (0.34) | PTGS2 | |
| SCHEMBL27812477 | 0.70 | CD44 (0.33) | — | |
| SCHEMBL8431692 | 0.68 | KMT2A (0.36) | P2RY4ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207252-B1 | AROMATIC HYDROXY- OR THIOL DERIVATIVES OF CARBONIC-ACID ESTERS AS LIPASE SUBSTRATES | Roche Diagnostics GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |
| US-4988497-A | Diagnostic test for acute pancreatitus or cancer of the pancreas; sensitivity; colorimetry S | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4847376-A | COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0207252-A2 | Aromatic hydroxy- or thiol derivatives of carbonic-acid esters as lipase substrates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |