Sulfuric Acid

SCHEMBL9705769

CC(=O)OC[C@H]1O[C@@](COC(C)=O)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O.[Ba]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	LDHA	P00338	1/20	0.36

▸	CYP2D6	P10635	1/20	0.35

▸	THRB	P10828	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	EPHX2	P34913	1/20	0.35

▸	CA2	P00918	10/20	0.34

▸	CA12	O43570	9/20	0.34

▸	CA1	P00915	9/20	0.34

▸	CA9	Q16790	7/20	0.34

▸	CD69	Q07108	1/20	0.34

▸	CA4	P22748	2/20	0.33

▸	CA5A	P35218	2/20	0.33

▸	CA7	P43166	2/20	0.33

▸	CA5B	Q9Y2D0	2/20	0.33

▸	CDK1	P06493	1/20	0.33

▸	CCNB1	P14635	1/20	0.33

▸	FGF1	P05230	1/20	0.33

▸	FGF2	P09038	1/20	0.33

▸	PKM	P14618	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2888526	0.95	CYP2D6 (0.38)	LDHACYP2D6THRBHSD17B10EPHX2
SCHEMBL4581260	0.89	CYP2D6 (0.41)	LDHACYP2D6THRBHSD17B10EPHX2
SCHEMBL3418341	0.89	CDK1 (0.43)	LDHACYP2D6THRBHSD17B10EPHX2
SCHEMBL8038328	0.85	CYP2D6 (0.47)	CYP2D6THRBHSD17B10CA2CA12
SCHEMBL1614946	0.84	CDK1 (0.42)	LDHAEPHX2CA2CA9CD69
SCHEMBL8939201	0.83	LDHA (0.43)	LDHACYP2D6THRBHSD17B10EPHX2
Sucrose Octaacetate SCHEMBL23549924	0.82	CYP2D6 (0.53)	CYP2D6THRBHSD17B10CA2CA12
Sucrose Octaacetate SCHEMBL48906	0.82	CYP2D6 (0.53)	CYP2D6THRBHSD17B10CA2CA12
Sucrose Octaacetate SCHEMBL16330227	0.82	CYP2D6 (0.53)	CYP2D6THRBHSD17B10CA2CA12
Sucrose Octaacetate SCHEMBL23549923	0.82	CYP2D6 (0.53)	CYP2D6THRBHSD17B10CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0230023-B1	PHARMACEUTICAL COMPOSITIONS FOR THE ENHANCEMENT OF WOUND HEALING	MARION MERRELL DOW INC. (US)	1992-09-02	—	—	EP	disclosed
US-4912093-A	Polysulfated (mono- or oligo-)saccharide	MARION LABORATORIES, INC. (US)	1990-03-27	—	—	US	disclosed
EP-0230023-A2	Pharmaceutical compositions for the enhancement of wound healing	MARION MERRELL DOW INC. (US)	1987-07-29	—	—	EP	disclosed