Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137745 | 0.88 | NR3C2 (0.47) | NR3C2CACNA1CMAPTCACNA1FCACNA1D | |
| SCHEMBL9549837 | 0.84 | NR3C2 (0.39) | NR3C2PSMB5MAPTPOLBKDM4E | |
| SCHEMBL9385237 | 0.83 | NR3C2 (0.42) | NR3C2CACNA1CPSMB5MAPTCACNA1F | |
| SCHEMBL9140284 | 0.83 | NR3C2 (0.44) | NR3C2CACNA1CMAPTCACNA1FCACNA1D | |
| SCHEMBL9205840 | 0.81 | KDM4E (0.48) | NR3C2CACNA1CMAPTKDM4ERAB9A | |
| SCHEMBL9139844 | 0.80 | NR3C2 (0.56) | NR3C2CACNA1CMAPTKDM4ENPSR1 | |
| SCHEMBL9463382 | 0.80 | NR3C2 (0.51) | NR3C2CACNA1CMAPTCACNA1FCACNA1D | |
| SCHEMBL9413455 | 0.78 | MAPT (0.38) | NR3C2CACNA1CMAPTPOLBCACNA1F | |
| SCHEMBL9200857 | 0.77 | MAPT (0.41) | NR3C2CACNA1CMAPTCACNA1FCACNA1D | |
| SCHEMBL9463271 | 0.76 | NR3C2 (0.44) | NR3C2PSMB5ALDH1A1NPSR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518105-A1 | 3-Formyl-1,4-dihydropyridines, process for their preparation and their pharmaceutical use | BAYER AG (DE) | 1992-12-16 | — | — | EP | disclosed |