Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 7/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.40 |
| ▸ | AXL | P30530 | 6/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580965 | 0.93 | CYP2C9 (0.48) | NR3C2AXLCAMKK2ALDH1A1HPGD | |
| SCHEMBL9580964 | 0.89 | CYP2C9 (0.51) | NR3C2AXLCAMKK2ALDH1A1HPGD | |
| SCHEMBL9463382 | 0.87 | NR3C2 (0.51) | NR3C2ALDH1A1HPGDNPSR1 | |
| SCHEMBL9385237 | 0.82 | NR3C2 (0.42) | NR3C2PSMB5GSK3AGSK3BAXL | |
| SCHEMBL8923705 | 0.81 | NR3C2 (0.52) | NR3C2METALDH1A1HTTNPSR1 | |
| SCHEMBL7162892 | 0.81 | NR3C2 (0.52) | NR3C2METALDH1A1HTTNPSR1 | |
| SCHEMBL9140284 | 0.81 | NR3C2 (0.44) | NR3C2AXLCAMKK2ALDH1A1HPGD | |
| SCHEMBL9467948 | 0.80 | NR3C2 (0.62) | NR3C2AXLMETALDH1A1HPGD | |
| SCHEMBL9137745 | 0.80 | NR3C2 (0.47) | NR3C2ALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL9139844 | 0.79 | NR3C2 (0.56) | NR3C2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262429-A | CARDIOTONIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-16 | — | — | US | disclosed |