Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705902 | 1.00 | NR1I2 (0.30) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9862967 | 0.87 | NPC1 (0.35) | MEN1KMT2A | |
| SCHEMBL9862966 | 0.87 | NPC1 (0.35) | MEN1KMT2A | |
| SCHEMBL9706281 | 0.84 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10420328 | 0.84 | KCNH2 (0.40) | MEN1KMT2A | |
| SCHEMBL9876059 | 0.84 | KCNH2 (0.40) | MEN1KMT2A | |
| Win-54954 SCHEMBL8755546 | 0.82 | NR1I2 (0.39) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705761 | 0.82 | NR1I2 (0.39) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705776 | 0.82 | NR1I2 (0.39) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9863024 | 0.80 | NR1I2 (0.30) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |