Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862966 | 1.00 | NPC1 (0.35) | NPC1RAB9AGRM2KMT2AMEN1 | |
| SCHEMBL9705896 | 0.87 | NR1I2 (0.30) | KMT2AMEN1 | |
| SCHEMBL9705902 | 0.87 | NR1I2 (0.30) | KMT2AMEN1 | |
| SCHEMBL9876059 | 0.85 | KCNH2 (0.40) | KMT2AMEN1SCARB1MAPTKDM4E | |
| SCHEMBL10420328 | 0.85 | KCNH2 (0.40) | KMT2AMEN1SCARB1MAPTKDM4E | |
| SCHEMBL9668279 | 0.84 | TDP1 (0.39) | NPC1RAB9AGRM2KMT2AMEN1 | |
| SCHEMBL9667163 | 0.83 | TDP1 (0.38) | NPC1RAB9AGRM2KMT2AMEN1 | |
| SCHEMBL9666735 | 0.83 | TDP1 (0.38) | NPC1RAB9AGRM2KMT2AMEN1 | |
| SCHEMBL9668088 | 0.83 | TDP1 (0.38) | NPC1RAB9AGRM2KMT2AMEN1 | |
| SCHEMBL9667744 | 0.83 | TDP1 (0.38) | NPC1RAB9AGRM2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |